Tag: aging

Senescence-associated lncRNAs indicate distinct molecular subtypes associated with prognosis and androgen response in patients with patients with prostate cancer

Announcing a new publication for Acta Materia Medica journal.  Cellular senescence has been considered as a hallmark of aging. The authors of this article aimed to establish two novel prognostic subtypes for prostate cancer patients using senescence-related lncRNAs. Nonnegative matrix factorization algorithm was used to identify molecular subtypes. Analyses were completed using software R 3.6.3 […]

Aging and cancer hallmarks as therapeutic targets

Announcing a new publication for Acta Materia Medica journal.  The prevalence of age-related diseases has been progressively increasing worldwide. The pathogenesis of these disorders, including cancer, is closely associated with an age-dependent decline in cellular functions. There are multiple layers of crosstalk between aging processes and oncogenesis. Therefore, a better understanding of the interplay between […]

Small-molecule fluorescence-based probes for aging diagnosis

This new review article summarizes recent research progress in small-molecule fluorescence-based probes for aging diagnosis, and further discusses the challenges and opportunities in this field. Aging is a time-dependent decline in physiological function that affects most organisms and is the major risk factor for many non-communicable diseases. The early diagnosis of aging is critical for […]