Announcing a new publication for Acta Materia Medica journal. Cancer is a formidable threat to human life, a cure for which in advanced stages remains challenging. Early detection and treatment of cancer are paramount, yet a substantial number of cancer patients receive diagnoses at an advanced stage, resulting in a lower 5-year survival rate. Early-stage […]
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Macrophage differentiation in enhancing hematopoietic function of ribonucleic acid for injection II via multi-omics analysis
Announcing a new publication for Acta Materia Medica journal. Ribonucleic acid for injection II is a clinical adjuvant cancer therapy treatment based on immunotherapy, which exerts its effects by enhancing immune function and suppressing tumor growth. However, the mechanism underlying the ameliorative effect on immunosuppressed hematopoietic dysfunction remains unclear. This study confirms the immune-boosting and […]
Multi-omics strategy reveals that Cordyceps Sinensis ameliorates sepsis-associated acute kidney injury via reprogramming of mitochondrial energy metabolism and macrophage polarization
Announcing a new publication for Acta Materia Medica journal. Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional medicine for the prevention, treatment, and prognostication of various diseases, because of its pleiotropic pharmacological properties. However, the potential pharmacological action of CS in sepsis-associated acute kidney injury (S-AKI) remains poorly understood. Herein, we […]
Protective role of the curcumin derivative FM0807,in regulating signaling pathways in glomerular mesangial cells and renal function in db db mice
Announcing a new publication for Acta Materia Medica journal. To determine the protective effects of FM0807 against diabetes-induced renal inflammation and fibrosis and the underlying mechanisms in vivo and in vitro. FM0807 was administered to db/db mice. Glomerular mesangial cells (HBZY-1) were cultured under high glucose conditions with or without FM0807. Gene and protein expression was assessed by […]
Pristimerin inhibits thioredoxin reductase in the treatment of non-small cell lung cancer
Announcing a new publication for Acta Materia Medica journal. Elevated cellular oxidative stress is a common marker of cancer cell dysregulation caused by malignant transformation. Thioredoxin reductase (TrxR, encoded by TXNRD) is a crucial enzyme that regulates cellular oxidative stress and the survival of many types of cancer cells. Therefore, targeting TrxR may lead to selective […]
Development and characterization of temperature-sensitive hydrogels embedded with sodium alginate-chitosan microspheres
Announcing a new publication for Acta Materia Medica journal. Ulcerative colitis (UC) is a chronic intestinal disorder characterized by severe intestinal inflammation and superficial mucosal ulcers. Ramulus mori alkaloids (SZ-A) were approved by the National Medical Products Administration of China in 2020 for the treatment of type 2 diabetes mellitus. Later studies confirmed that SZ-A […]
The KIT ligand KITLG promotes portal vein tumor thrombosis by up-regulating COL4A1 through STAT3-SMAD2 signaling in hepatocellular carcinoma
Announcing a new publication for Acta Materia Medica journal. Portal vein tumor thrombosis (PVTT), a severe complication of hepatocellular carcinoma (HCC), markedly influences patient prognosis by fostering a hypercoagulable state. However, its molecular underpinnings remain largely unexplored. This study sheds light on the critical role of the KIT ligand (KITLG) in modulating expression of the […]
Role of natural products in tumor therapy from basic research and clinical perspectives
Announcing a new publication for Acta Materia Medica journal. Cancer is the leading cause of morbidity and mortality worldwide and is an important barrier to lengthening life expectancy in every country. Natural products are receiving increased attention from researchers globally and increasing numbers of natural products are approved for clinical studies involving cancer in recent […]
Acta Materia Medica now indexed by SCOPUS
We are happy to announce this very good news to all authors, editors, reviewers and readers. Acta Materia Medica will be indexed by SCOPUS from May 27th, 2024. The bibliographic database managed by Elsevier covers high-ranking peer-reviewed journals in the technical, medical and social sciences. On this occasion, congratulations to Professor Hongxi Xu and Professor […]
The andrographolide derivative, AND7, and TRAIL combination attenuates acute lymphoblastic leukemia through P53-regulated ROS accumulation
Announcing a new publication for Acta Materia Medica journal. Acute lymphoblastic leukemia (ALL) is a malignant disease of the hematologic system. The current treatment is based on chemotherapeutic drugs, which are becoming less effective due to drug resistance. TNF-related apoptosis-inducing ligand (TRAIL) is an apoptotic protein used to treat cancer that does not affect healthy […]