Category: News and Events

Effects of B-carotene on glucose metabolism dysfunction in humans and type 2 diabetic rats

Announcing a new review article publication for Acta Materia Medica journal. Type 2 diabetes mellitus (T2DM) is a common chronic disease that is strongly associated with cardiovascular risk. Long-term high blood glucose levels may induce cardiomyocyte apoptosis, cardiac dysfunction and suppress fetal cardiomyocyte proliferation. Recent epidemiological studies have shown a link between antioxidant carotenoids and […]

Research progress in 3D-printed medicinal tablets

Announcing a new review article publication for Acta Materia Medica journal.  Three-dimensional printing (3DP) is a rapid-prototyping technology that uses a digital model file to construct an object through layer printing. This novel technology is widely used in aerospace, medicine, architecture and industrial applications. However, the pharmaceutical applications of 3DP technology remain in early stages, […]

Prognosis and treatment of complications associated with COVID-19: a systematic review and meta-analysis

Announcing a new review article publication for Acta Materia Medica journal. The Coronavirus Disease 2019 (COVID-19) pandemic has been estimated to have claimed more than 6 million lives, and most deaths have been attributed to complications non-specific to the virus. Therefore, understanding and treating these complications are imperative. In this paper the authors review 181 […]

Ligands for oral delivery of peptides across the blood-brain-barrier

Announcing a new review article publication for Acta Materia Medica journal. Peptides are short chains of amino acids linked by peptide bonds. Many peptides and proteins are limited by their poor enzymatic stability and permeability across the intestinal epithelial membranes and/or blood-brain barrier (BBB). Parenteral administration of these peptides is unfavorable because of procedural complications […]

Regulatory lessons from China’s COVID-19 vaccines development and approval policies

Announcing a new review article publication for Acta Materia Medica journal. Coronavirus disease 2019, responsible for a global pandemic, is caused by the severe acute respiratory syndrome coronavirus 2. Several vaccines have been developed and approved worldwide, particularly in China. As of Oct 17, 2021, four new coronavirus vaccines in China have been conditionally approved […]

Structural diversity and biological activities of caged Garcinia xanthones: recent updates

Announcing a new review article publication for Acta Materia Medica journal. Caged xanthones are a class of natural compounds with approximately 200 members that are commonly isolated from the Garcinia genus in the Clusiaceae (formerly Guttiferae) family. They are often characterized by a notable 4-oxatricyclo[ 4.3.1.03,7]dec-2-one (caged) architecture with a common xanthone backbone. Because most […]

Advances In Therapeutic Agents Targeting Quiescent Cancer Cells

Announcing a new review article publication for Acta Materia Medica journal. Quiescent cancer cells (QCCs) reversibly reside in G0 phase, thus allowing them to survive chemotherapy and radiotherapy, which generally target proliferating cells. Surviving QCCs may re-proliferate, and consequently result in cancer progression, recurrence, and metastasis. Therefore, understanding the key players governing QCC survival and […]

Regulation of Neuronal Autophagy and Cell Survival by MCL1 in Alzheimer’s Disease

Announcing a new review article publication for Acta Materia Medica journal. In this review article, the authors discuss the emerging neuroprotective function of MCL1 and how dysregulation of MCL1 signaling is involved in the pathogenesis of AD. Because members of the pro-survival BCL2 family proteins are promising targets of pharmacological intervention with BH3 mimetic drugs, […]

PROTAC Technology for the Treatment of Alzheimer’s Disease: Advances and Perspectives

Announcing a new review article publication for Acta Materia Medica journal. Although PROTAC technology is preferable to oligonucleotides and antibodies for the treatment of neurodegenerative diseases, many limitations, such as their pharmacokinetic properties, tissue distribution, and cell permeability, must be addressed. The authors of this article review recent advances in PROTAC technology, as well as […]

Small-molecule fluorescence-based probes for aging diagnosis

This new review article summarizes recent research progress in small-molecule fluorescence-based probes for aging diagnosis, and further discusses the challenges and opportunities in this field. Aging is a time-dependent decline in physiological function that affects most organisms and is the major risk factor for many non-communicable diseases. The early diagnosis of aging is critical for […]