Announcing a new publication for Acta Materia Medica journal. Diabetic kidney disease (DKD) is one of the leading causes of end-stage renal disease. Verbascoside is a ubiquitous phenylethanoid glycoside with potent anti-inflammatory, antioxidant, and hypoglycemic properties. This paper determines the renoprotective effect of verbascoside against DKD, as well as the underlying mechanism. After administration of […]
Category: News and Events
Acta Materia Medica Call for Papers
Acta Materia Medica provides an open platform for rapid publication of the latest findings, approaches, and viewpoints related to all related areas of pharmacy and pharmaceutical sciences, including, but are not limited to, pharmacology, toxicology, pharmaceutics, medicinal chemistry, natural products, pharmacognosy, pharmaceutical analysis, pharmacokinetics, clinical pharmacy, pharmacoepidemiology, pharmacoeconomics and pharmacy management. Article types accepted: Research […]
Smart stimuli-responsive carrier-free nanoassembly of SN38 prodrug as efficient chemotherapeutic nanomedicine
Announcing a new publication for Acta Materia Medica journal. The compound 7-ethyl-10-hydroxy-camptothecin (SN38) is a broad-spectrum antitumor agent whose applications are greatly limited by its poor solubility. Therefore, irinotecan, the hydrophilic derived prodrug of SN38, has been developed as the commercial formulation Campto® for colorectal cancer. However, only 1% to 0.1% of irinotecan is converted to […]
Organoid models for Chinese herbal medicine studies
Announcing a new publication for Acta Materia Medica journal. Organoids are three-dimensional cell accusations generated from pluripotent stem cells or adult stem cells in vitro. With many advantages over cell and animal models, organoids have been increasingly used in drug and clinical medical research in recent years. Chinese herbal medicine (CHM) is characterized by multi-target and […]
Computational strategies for PROTAC drug discovery
Announcing a new publication for Acta Materia Medica journal. Proteolysis-targeting chimeras (PROTACs), a novel targeted protein degradation technology for potential clinical drug discovery, is composed of a protein-targeting ligand covalently linked to an E3 ligase ligand. Through recruiting E3 ligase to target proteins, PROTACs elicit ubiquitination and subsequent degradation of targets via the ubiquitin-proteasome system. […]
Recent advances in nano-targeting drug delivery systems for rheumatoid arthritis treatment
Announcing a new publication for Acta Materia Medica journal. Rheumatoid arthritis is a systemic inflammatory disease that can lead to articular cartilage destruction and periarticular bone erosion, thus ultimately compromising joint integrity and function. Anti-inflammatory drugs and biological agents are commonly used to treat rheumatoid arthritis, but they cannot selectively target inflamed joints, because of […]
Efficacy of corticosteroids as an adjunctive therapy in the treatment of community-acquired pneumonia
Announcing a new publication for Acta Materia Medica journal. The objective of this study was to systematically evaluate the clinical efficacy of the complementary use of corticosteroids in the treatment of community-acquired pneumonia (CAP). The authors searched all relevant documents in five scientific databases from inception to June 2022 to collect clinical trials (randomized controlled […]
Latent herpes simplex virus type 1 reactivation increases the susceptibility of neurodegenerative diseases intervention with traditional Chinese medicine
Announcing a new publication for Acta Materia Medica journal. Owing to environmental and lifestyle changes in modern society, physical and mental stress is on the rise among the population in attempting to compensate for the changes. Stress, defined as a series of non-specific responses to abnormal internal and external stimuli, has long been recognized to […]
Advances in microneedle patches for long-acting contraception
Announcing a new publication for Acta Materia Medica journal. Despite the advances in contraceptives, there is still a high rate of unintended pregnancies worldwide, due in large part to the lack of effective, convenient, and safe birth control methods. Compared with short-acting contraceptives, approaches that offer long-term pregnancy protection have attracted greater interest because of […]
Mass spectrometry imaging advances and application in pharmaceutical research
Announcing a new publication for Acta Materia Medica journal. Mass spectrometry imaging (MSI) has been shown to be a valuable tool through nearly every stage of the preclinical drug research and development (R&D) pipeline, and even to the early phase of clinical pharmaceutical evaluation. MSI can specifically resolve distributions of a parent drug and its […]