Announcing a new publication for Acta Materia Medica journal. Platelets are blood components traditionally believed to have fundamental roles in vascular hemostasis and thrombosis. In recent years, platelets have received new attention for their roles in tumorigenesis and progression. On the one hand, platelets are actively recruited by various tumors and comprise a crucial part […]
Category: News and Events
Emerging role of HJURP as a therapeutic target in cancers
Announcing a new publication for Acta Materia Medica journal. Holliday junction recognition protein (HJURP) is a key molecular chaperone for centromere protein A (CENP-A), which is essential for chromosome separation during mitosis and cell cycle regulation. Recent studies have identified the essential role of HJURP in carcinogenesis. Abnormal upregulation of HJURP expression has been observed […]
Inhalable ciprofloxacin/polymyxin B dry powders in respiratory infection therapy
Announcing a new publication for Acta Materia Medica journal. This study focuses on the formulation, physicochemical characterization, and antibacterial susceptibility testing of inhalable spray dried powders containing ciprofloxacin (CIP) and polymyxin B sulfate (PMB). CIP nanosuspensions with an average particle diameter of 435.9 ± 9.3 nm were initially obtained using the wet-milling protocol and subsequently […]
Acta Materia Medica (AMM) Editorial Board Meeting
First “i-Drug Discovery” International Innovative Drug Development Summit Forum These events brought a surge of pharmaceutical academic enthusiasm to Shanghai on March 18th, 2023. AMM invited numerous senior and young experts to gather, including Professor Hongxi Xu from Shanghai University of Traditional Chinese Medicine, Professor Jian Li from East China University of […]
Acta Materia Medica Call for Papers
The Co-Editors-in-Chief of Acta Materia Medica (AMM), Hongxi Xu, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China and Wenyi Wei, Harvard Medical School, Boston, MA, USA invite you to submit an article to the journal. Acta Materia Medica provides an open platform for rapid publication of the latest findings, approaches, and viewpoints […]
Molecular networking as a natural products discovery strategy
Announcing a new publication for Acta Materia Medica journal. The rapid development of bioinformatics tools has recently broken through the bottleneck in natural products research. These advances have enabled natural products researchers to rapidly separate and efficiently target and discover previously undescribed molecules. Among these advances, tandem mass spectrometry molecular networking is a promising method […]
Multi-component Chinese medicine formulas for drug discovery: State of the art and future perspectives
Announcing a new publication for Acta Materia Medica journal. For many years, the drug discovery and development industry has aimed at identifying single components with a clear mechanism of action as desirable candidates for potential drugs. However, this conventional strategy of drug discovery and development has faced challenges including a low success rate and high […]
Discovery of a pyridophenoselenazinium-based photosensitizer with high photodynamic efficacy against breast cancer cells
Announcing a new publication for Acta Materia Medica journal. Development of efficient photosensitizers with minimal side effects is highly desirable for photodynamic therapy. This article reports the discovery of a novel pyridophenoselenazinium-based NIR-I photosensitizer, termed PPSe, that efficiently generated both type I and II reactive oxygen species (ROS) upon appropriate light irradiation. PPSe exhibited potent phototoxicity as well […]
Potential pharmacokinetic interactions in fixed-dose combinations of perindopril/indapamide/amlodipine compared with perindopril/indapamide and amlodipine in healthy Chinese volunteers
Announcing a new publication for Acta Materia Medica journal. S05590 is a fixed-dose combination of perindopril tert-butylamine 4 mg/indapamide 1.25 mg, and S06593 is a fixed-dose combination of perindopril arginine 5 mg/indapamide 1.25 mg/amlodipine 5 mg. The purpose of this study was to determine whether pharmacokinetic interactions exist among the components of S06593, compared with […]
Phenylethanoid glycoside verbascoside ameliorates podocyte injury of diabetic kidney disease by regulating NR4A1-LKB1-AMPK signaling
Announcing a new publication for Acta Materia Medica journal. Diabetic kidney disease (DKD) is one of the leading causes of end-stage renal disease. Verbascoside is a ubiquitous phenylethanoid glycoside with potent anti-inflammatory, antioxidant, and hypoglycemic properties. This paper determines the renoprotective effect of verbascoside against DKD, as well as the underlying mechanism. After administration of […]