This new review article summarizes recent research progress in small-molecule fluorescence-based probes for aging diagnosis, and further discusses the challenges and opportunities in this field. Aging is a time-dependent decline in physiological function that affects most organisms and is the major risk factor for many non-communicable diseases. The early diagnosis of aging is critical for the treatment of aging and aging-related diseases. In recent years, extensive efforts have attempted to accurately diagnose aging. To date, multiple types of fluorescent probes for various age-related biomarkers have been developed, with the aims of achieving rapid, precise diagnosis of the aging process and evaluating the efficacy of anti-aging drugs.
Keywords: fluorescent probes, aging, senescence, diagnosis for aging, age-related biomarkers
Article Reference: Donglei Shi, Wenwen Liu and Guangwei Wang et al. Small-molecule fluorescence-based probes for aging diagnosis. Acta Materia Medica. Vol. 1(1). DOI: 10.15212/AMM-2021-0004
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