Announcing a new publication for Acta Materia Medica journal. Cellular senescence has been considered as a hallmark of aging. The authors of this article aimed to establish two novel prognostic subtypes for prostate cancer patients using senescence-related lncRNAs. Nonnegative matrix factorization algorithm was used to identify molecular subtypes. Analyses were completed using software R 3.6.3 […]
Category: News and Events
Recent advances in the molecular design and applications of proteolysis targeting chimera-based multi-specific antiviral modality
Announcing a new publication for Acta Materia Medica journal. Viral infections represent a major threat to human health and the global economy; however, most of the currently available antiviral drugs are not fully effective in restricting viral replication and selecting for drug-resistant variants. Targeted protein degradation technologies are promising strategies to avoid or delay the […]
Aging and cancer hallmarks as therapeutic targets
Announcing a new publication for Acta Materia Medica journal. The prevalence of age-related diseases has been progressively increasing worldwide. The pathogenesis of these disorders, including cancer, is closely associated with an age-dependent decline in cellular functions. There are multiple layers of crosstalk between aging processes and oncogenesis. Therefore, a better understanding of the interplay between […]
1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein
Announcing a new publication for Acta Materia Medica journal. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally since 2020. The nucleocapsid (N) protein plays a crucial role in the life cycle of SARS-CoV-2. The authors of this article have established a method to screen inhibitors of N protein by using microscale thermophoresis assays […]
ZnPc photosensitizer-loaded peony-shaped FeSe 2 remotely controlled by near-infrared light for antimycobacterial therapy
Announcing a new publication for Acta Materia Medica journal. The development of novel antimicrobial agents is highly desirable for treating bacterial infections. The authors of this article constructed a smart photodynamic therapy (PDT) system based on a combination of peony-shaped ferroselite FeSe2 particles and zinc (II) phthalocyanine (ZnPc) photosensitizers. Effective energy transfer occurred from ZnPc to […]
STING agonist delivery by lipid calcium phosphate nanoparticles enhances immune activation for neuroblastoma
Announcing a new publication for Acta Materia Medica journal. Neuroblastoma (NB) is a common solid tumor in children and infants, the formation and regression of which is closely linked to the tumor-host immune relationship. Stimulator of interferon genes (STING) agonists, particularly cyclic dinucleotide (CDN), have promising potential in NB therapy by generating innate and adaptive […]
Efgartigimod, an FcRn antagonist, as a potential treatment for post COVID-19 syndrome
Announcing a new publication for Acta Materia Medica journal. A significant proportion of patients who survive COVID-19 develop a constellation of life-altering symptoms that persist long after the initial infection has resolved. This post-COVID-19 syndrome may result from the development of autoreactive IgG antibodies that cause inflammation and tissue injury. The authors of this article […]
Biological functions and therapeutic potential of acylation by histone acetyltransferases
Announcing a new publication for Acta Materia Medica journal. Histone lysine acylation is a major class of histone post-translational modifications involved in essential biological activities, such as transcriptional regulation, DNA-damage repair, and cell-cycle progression. Abnormal acylation is strongly associated with various diseases, such as cancer. Thus, histone acetyltransferases (HATs), the “writers” that catalyze histone acylation, […]
Animal models of Alzheimer’s disease: preclinical insights and challenges
Announcing a new publication for Acta Materia Medica journal. Alzheimer’s disease (AD), an irreversible neurodegenerative disease that progressively impairs memory and cognitive judgment, severely affects the quality of life and imposes a heavy burden on the healthcare system. No cure is currently available for AD, in part because the pathogenesis of this disease has not […]
Acta Materia Medica Call for Papers
Platinum open access journal – no APCs during 2023 Fast publication times The Co-Editors-in-Chief of Acta Materia Medica (AMM), Hongxi Xu, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China and Wenyi Wei, Harvard Medical School, Boston, MA, USA invite you to submit an article to the journal. Acta Materia Medica provides an open […]