The Co-Editors-in-Chief of Acta Materia Medica (AMM), Hongxi Xu, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China and Wenyi Wei, Harvard Medical School, Boston, MA, USA invite you to submit an article to the journal. Acta Materia Medica provides an open platform for rapid publication of the latest findings, approaches, and viewpoints […]
Category: News and Events
Molecular networking as a natural products discovery strategy
Announcing a new publication for Acta Materia Medica journal. The rapid development of bioinformatics tools has recently broken through the bottleneck in natural products research. These advances have enabled natural products researchers to rapidly separate and efficiently target and discover previously undescribed molecules. Among these advances, tandem mass spectrometry molecular networking is a promising method […]
Multi-component Chinese medicine formulas for drug discovery: State of the art and future perspectives
Announcing a new publication for Acta Materia Medica journal. For many years, the drug discovery and development industry has aimed at identifying single components with a clear mechanism of action as desirable candidates for potential drugs. However, this conventional strategy of drug discovery and development has faced challenges including a low success rate and high […]
Discovery of a pyridophenoselenazinium-based photosensitizer with high photodynamic efficacy against breast cancer cells
Announcing a new publication for Acta Materia Medica journal. Development of efficient photosensitizers with minimal side effects is highly desirable for photodynamic therapy. This article reports the discovery of a novel pyridophenoselenazinium-based NIR-I photosensitizer, termed PPSe, that efficiently generated both type I and II reactive oxygen species (ROS) upon appropriate light irradiation. PPSe exhibited potent phototoxicity as well […]
Potential pharmacokinetic interactions in fixed-dose combinations of perindopril/indapamide/amlodipine compared with perindopril/indapamide and amlodipine in healthy Chinese volunteers
Announcing a new publication for Acta Materia Medica journal. S05590 is a fixed-dose combination of perindopril tert-butylamine 4 mg/indapamide 1.25 mg, and S06593 is a fixed-dose combination of perindopril arginine 5 mg/indapamide 1.25 mg/amlodipine 5 mg. The purpose of this study was to determine whether pharmacokinetic interactions exist among the components of S06593, compared with […]
Phenylethanoid glycoside verbascoside ameliorates podocyte injury of diabetic kidney disease by regulating NR4A1-LKB1-AMPK signaling
Announcing a new publication for Acta Materia Medica journal. Diabetic kidney disease (DKD) is one of the leading causes of end-stage renal disease. Verbascoside is a ubiquitous phenylethanoid glycoside with potent anti-inflammatory, antioxidant, and hypoglycemic properties. This paper determines the renoprotective effect of verbascoside against DKD, as well as the underlying mechanism. After administration of […]
Acta Materia Medica Call for Papers
Acta Materia Medica provides an open platform for rapid publication of the latest findings, approaches, and viewpoints related to all related areas of pharmacy and pharmaceutical sciences, including, but are not limited to, pharmacology, toxicology, pharmaceutics, medicinal chemistry, natural products, pharmacognosy, pharmaceutical analysis, pharmacokinetics, clinical pharmacy, pharmacoepidemiology, pharmacoeconomics and pharmacy management. Article types accepted: Research […]
Smart stimuli-responsive carrier-free nanoassembly of SN38 prodrug as efficient chemotherapeutic nanomedicine
Announcing a new publication for Acta Materia Medica journal. The compound 7-ethyl-10-hydroxy-camptothecin (SN38) is a broad-spectrum antitumor agent whose applications are greatly limited by its poor solubility. Therefore, irinotecan, the hydrophilic derived prodrug of SN38, has been developed as the commercial formulation Campto® for colorectal cancer. However, only 1% to 0.1% of irinotecan is converted to […]
Organoid models for Chinese herbal medicine studies
Announcing a new publication for Acta Materia Medica journal. Organoids are three-dimensional cell accusations generated from pluripotent stem cells or adult stem cells in vitro. With many advantages over cell and animal models, organoids have been increasingly used in drug and clinical medical research in recent years. Chinese herbal medicine (CHM) is characterized by multi-target and […]
Computational strategies for PROTAC drug discovery
Announcing a new publication for Acta Materia Medica journal. Proteolysis-targeting chimeras (PROTACs), a novel targeted protein degradation technology for potential clinical drug discovery, is composed of a protein-targeting ligand covalently linked to an E3 ligase ligand. Through recruiting E3 ligase to target proteins, PROTACs elicit ubiquitination and subsequent degradation of targets via the ubiquitin-proteasome system. […]