Announcing a new review article publication for Acta Materia Medica journal. Caged xanthones are a class of natural compounds with approximately 200 members that are commonly isolated from the Garcinia genus in the Clusiaceae (formerly Guttiferae) family. They are often characterized by a notable 4-oxatricyclo[ 4.3.1.03,7]dec-2-one (caged) architecture with a common xanthone backbone. Because most […]
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Advances In Therapeutic Agents Targeting Quiescent Cancer Cells
Announcing a new review article publication for Acta Materia Medica journal. Quiescent cancer cells (QCCs) reversibly reside in G0 phase, thus allowing them to survive chemotherapy and radiotherapy, which generally target proliferating cells. Surviving QCCs may re-proliferate, and consequently result in cancer progression, recurrence, and metastasis. Therefore, understanding the key players governing QCC survival and […]
Regulation of Neuronal Autophagy and Cell Survival by MCL1 in Alzheimer’s Disease
Announcing a new review article publication for Acta Materia Medica journal. In this review article, the authors discuss the emerging neuroprotective function of MCL1 and how dysregulation of MCL1 signaling is involved in the pathogenesis of AD. Because members of the pro-survival BCL2 family proteins are promising targets of pharmacological intervention with BH3 mimetic drugs, […]
PROTAC Technology for the Treatment of Alzheimer’s Disease: Advances and Perspectives
Announcing a new review article publication for Acta Materia Medica journal. Although PROTAC technology is preferable to oligonucleotides and antibodies for the treatment of neurodegenerative diseases, many limitations, such as their pharmacokinetic properties, tissue distribution, and cell permeability, must be addressed. The authors of this article review recent advances in PROTAC technology, as well as […]
Small-molecule fluorescence-based probes for aging diagnosis
This new review article summarizes recent research progress in small-molecule fluorescence-based probes for aging diagnosis, and further discusses the challenges and opportunities in this field. Aging is a time-dependent decline in physiological function that affects most organisms and is the major risk factor for many non-communicable diseases. The early diagnosis of aging is critical for […]
Drug Discovery is an Eternal Challenge for the Biomedical Sciences
In this inaugural Editorial the Co-Editors-in-Chief and Executive Editor of Acta Materia Medica Hua Li Wenyi Wei and Hongxi Xu discuss how drug discovery is an eternal challenge for the biomedical sciences. The discovery of new drugs is among humanity’s most sophisticated and cutting-edge intellectual activities. This process requires not only the discovery of the […]
Announcing a New Journal: Acta Materia Medica
Shannon, November 16, 2021 — Compuscript is delighted to announce the launch of a new academic journal, Acta Materia Medica. Acta Materia Medica provides an open platform for rapid publication of the latest findings, approaches, and viewpoints related to all related areas of pharmacy and pharmaceutical sciences, including, but are not limited to, pharmacology, toxicology, […]