Announcing a new review article publication for Acta Materia Medica journal. Cancer is a consequence of uncontrolled cell proliferation that is associated with cell-cycle disruption. It is a multifactorial disease that depends on the modulation of numerous oncogenic signaling pathways and targets and is a major cause of death worldwide. Because of the development of […]
Category: News and Events
Structure prediction of the entire proteome of monkeypox variants
Announcing a new review article publication for Acta Materia Medica journal. Recently, the monkeypox virus has begun to spread in many countries worldwide. The genome sequence of the monkeypox virus variant responsible for the current outbreak has been reported, thus providing an important resource for better understanding the new variant and accelerating vaccine and drug […]
Acta Materia Medica Meets with the Experts Antibacterial and Antitumor Activities of Metal Complexes and their Mechanisms
Acta Materia Medica hosted an online webinar, ‘Antibacterial and Antitumor Activities of Metal Complexes and their Mechanisms’ on Thursday June 9 2022. Presenter: Professor Wei Xia, Sun Yat-sen University, Guangzhou, China Wei Xia received his B.S. degree from Peking University in 2006 and Ph.D. degree from the University of Hong Kong in 2011. From 2011 […]
PROTAC degraders with ligands recruiting MDM2 E3 ubiquitin ligase: an updated perspective
Announcing a new review article publication for Acta Materia Medica journal. Mouse double minute 2 (MDM2) is an oncogenic E3 ligase that effectively degrades the tumor suppressor p53. In the past two decades, many MDM2 inhibitors that disrupt MDM2-p53 binding have been discovered and developed. Given that MDM2 and p53 form an auto-regulatory loop, in […]
Discovery and characterization of naturally occurring chalcones as potent inhibitors of bile salt hydrolases
Announcing a new review article publication for Acta Materia Medica journal. Bile salt hydrolases (BSHs) play crucial roles in the deconjugation of conjugated bile acids and therefore are key targets for modulating bile acid metabolism. This authors of this article aimed to identify efficacious BSH inhibitors from a natural compound library and to characterize their […]
Effects of B-carotene on glucose metabolism dysfunction in humans and type 2 diabetic rats
Announcing a new review article publication for Acta Materia Medica journal. Type 2 diabetes mellitus (T2DM) is a common chronic disease that is strongly associated with cardiovascular risk. Long-term high blood glucose levels may induce cardiomyocyte apoptosis, cardiac dysfunction and suppress fetal cardiomyocyte proliferation. Recent epidemiological studies have shown a link between antioxidant carotenoids and […]
Research progress in 3D-printed medicinal tablets
Announcing a new review article publication for Acta Materia Medica journal. Three-dimensional printing (3DP) is a rapid-prototyping technology that uses a digital model file to construct an object through layer printing. This novel technology is widely used in aerospace, medicine, architecture and industrial applications. However, the pharmaceutical applications of 3DP technology remain in early stages, […]
Prognosis and treatment of complications associated with COVID-19: a systematic review and meta-analysis
Announcing a new review article publication for Acta Materia Medica journal. The Coronavirus Disease 2019 (COVID-19) pandemic has been estimated to have claimed more than 6 million lives, and most deaths have been attributed to complications non-specific to the virus. Therefore, understanding and treating these complications are imperative. In this paper the authors review 181 […]
Ligands for oral delivery of peptides across the blood-brain-barrier
Announcing a new review article publication for Acta Materia Medica journal. Peptides are short chains of amino acids linked by peptide bonds. Many peptides and proteins are limited by their poor enzymatic stability and permeability across the intestinal epithelial membranes and/or blood-brain barrier (BBB). Parenteral administration of these peptides is unfavorable because of procedural complications […]
Regulatory lessons from China’s COVID-19 vaccines development and approval policies
Announcing a new review article publication for Acta Materia Medica journal. Coronavirus disease 2019, responsible for a global pandemic, is caused by the severe acute respiratory syndrome coronavirus 2. Several vaccines have been developed and approved worldwide, particularly in China. As of Oct 17, 2021, four new coronavirus vaccines in China have been conditionally approved […]