Prognosis and treatment of complications associated with COVID-19: a systematic review and meta-analysis

Announcing a new review article publication for Acta Materia Medica journal. The Coronavirus Disease 2019 (COVID-19) pandemic has been estimated to have claimed more than 6 million lives, and most deaths have been attributed to complications non-specific to the virus. Therefore, understanding and treating these complications are imperative.

In this paper the authors review 181 studies published in early stages of the COVID-19 pandemic. The complications with high incidence among all COVID-19 cases were acute respiratory distress syndrome (ARDS, 18.52%), respiratory failure (16.54%), liver injury (14.13%) and multiple-organ dysfunction syndrome (MODS, 13.62%). Among patients who died, the most common complications were ARDS (84.10%), respiratory failure (78.75%) and respiratory injury (75.72%).

The authors of this article analyze the risk factors for complications, and review the currently available therapies according to complications and prognosis. To decrease the prevalence of COVID-19 complications and mortality, healthcare workers and patients should consider the complications identified, particularly those occurring preclinically.

Article Reference: Xudong Xie, Liangcong Hu and Hang Xue et al. Prognosis and treatment of complications associated with COVID-19: a systematic review and meta-analysis. Acta Materia Medica. Vol. 1(1):124-137. DOI: 10.15212/AMM-2022-0002

Keywords: COVID-19, SARS-CoV-2, complications, prognosis, treatment

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