Tag: photodynamic therapy

Discovery of a pyridophenoselenazinium-based photosensitizer with high photodynamic efficacy against breast cancer cells

Announcing a new publication for Acta Materia Medica journal.  Development of efficient photosensitizers with minimal side effects is highly desirable for photodynamic therapy. This article reports the discovery of a novel pyridophenoselenazinium-based NIR-I photosensitizer, termed PPSe, that efficiently generated both type I and II reactive oxygen species (ROS) upon appropriate light irradiation. PPSe exhibited potent phototoxicity as well […]

Recent progress in cancer therapy based on the combination of ferroptosis with photodynamic therapy

Announcing a new publication for Acta Materia Medica journal. Current anticancer treatments have many limitations to achieving high efficacy. Hence, novel strategies that broaden therapeutic prospects must urgently be developed. Ferroptosis is an iron-dependent form of non-apoptotic programmed cell death that is induced by cellular antioxidative system inhibition. Photodynamic therapy (PDT) uses photosensitizers to generate […]