Tag: PAs

Drug-like properties of serial phenanthroindolizidine alkaloid compounds: ADMET characteristic prediction and validation

Announcing a new publication for Acta Materia Medica journal.  Phenanthroindolizidine alkaloids (PAs) are a series of compounds that have been isolated from traditional herbal medicines and have significant therapeutic potential, such as anti-arthritic, anti-viral, anti-inflammatory, and anti-glioma effects in vitro and in vivo. This study predicts the absorption, distribution, metabolism, excretion, and toxicity (ADMET) characteristics of 44 compounds in […]