Tag: mitochondria

Effects of B-carotene on glucose metabolism dysfunction in humans and type 2 diabetic rats

Announcing a new review article publication for Acta Materia Medica journal. Type 2 diabetes mellitus (T2DM) is a common chronic disease that is strongly associated with cardiovascular risk. Long-term high blood glucose levels may induce cardiomyocyte apoptosis, cardiac dysfunction and suppress fetal cardiomyocyte proliferation. Recent epidemiological studies have shown a link between antioxidant carotenoids and […]

Regulation of Neuronal Autophagy and Cell Survival by MCL1 in Alzheimer’s Disease

Announcing a new review article publication for Acta Materia Medica journal. In this review article, the authors discuss the emerging neuroprotective function of MCL1 and how dysregulation of MCL1 signaling is involved in the pathogenesis of AD. Because members of the pro-survival BCL2 family proteins are promising targets of pharmacological intervention with BH3 mimetic drugs, […]