Tag: inhibitor

Discovery and characterization of naturally occurring chalcones as potent inhibitors of bile salt hydrolases

Announcing a new review article publication for Acta Materia Medica journal.  Bile salt hydrolases (BSHs) play crucial roles in the deconjugation of conjugated bile acids and therefore are key targets for modulating bile acid metabolism. This authors of this article aimed to identify efficacious BSH inhibitors from a natural compound library and to characterize their […]