Tag: inflammation

Protective role of the curcumin derivative FM0807,in regulating signaling pathways in glomerular mesangial cells and renal function in db db mice

Announcing a new publication for Acta Materia Medica journal.  To determine the protective effects of FM0807 against diabetes-induced renal inflammation and fibrosis and the underlying mechanisms in vivo and in vitro. FM0807 was administered to db/db mice. Glomerular mesangial cells (HBZY-1) were cultured under high glucose conditions with or without FM0807. Gene and protein expression was assessed by […]

Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates

Announcing a new publication for Acta Materia Medica journal.  Inflammation is an essential part of the immune response to injury and infection. Emerging evidence indicates that long-term low-grade inflammation is positively correlated with many diseases, such as cancer, metabolic disorders, and cardiovascular diseases. Due to common anti-inflammatory drugs are suitable for treating acute inflammation and […]

Recent advances in nano-targeting drug delivery systems for rheumatoid arthritis treatment

Announcing a new publication for Acta Materia Medica journal.  Rheumatoid arthritis is a systemic inflammatory disease that can lead to articular cartilage destruction and periarticular bone erosion, thus ultimately compromising joint integrity and function. Anti-inflammatory drugs and biological agents are commonly used to treat rheumatoid arthritis, but they cannot selectively target inflamed joints, because of […]