Tag: drug resistance

How new drug R&D can solve intractable scientific problems and meet clinical needs: insights from analysis of typical use cases

Announcing a new publication for Acta Materia Medica journal.  New drug research and development (R&D) faces critical challenges such as drug resistance, ineffectiveness of single-target interventions, “undruggable” targets, long cycles, and high costs. This article analyzes five typical use cases to illustrate breakthrough strategies for addressing these issues. Innovations include the identification of dual-target antibiotics […]

Ferroptosis by nanomaterials: targeting cancer stem cells and overcoming drug resistance

Ferroptosis by nanomaterials

Announcing a new publication for Acta Materia Medica journal. Tumor ferroptosis, a regulated form of cell death driven by iron-dependent lipid peroxidation, has emerged as a promising therapeutic strategy for combating cancers, particularly in cases involving cancer stem cells (CSCs) and drug resistance. In recent years nanomaterial-based approaches have gained significant attention for the potential […]