Tag: Drug Development

Artificial intelligence in Traditional Chinese Medicine: systematic insights from data mining, large language models, and multimodal fusion

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Announcing a new publication for Acta Materia Medica journal. Traditional Chinese medicine (TCM), characterized by multi-component, multi-target, and systemic therapeutic mechanisms, provides unique advantages in managing complex diseases. However, the inherent complexity of TCM formulations, including nonlinear component interactions, elusive compatibility principles, and a lack of quantitative biomarkers, has hindered the systematic elucidation of their […]

Solving the mysteries of urate transport: structural insights into GLUT9 and URAT1

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Announcing a new publication for Acta Materia Medica journal. Recent groundbreaking advances in the structural biology of the glucose transporter 9 (GLUT9) and urate transporter 1 (URAT1) have provided critical insights into the molecular mechanisms underlying urate recognition and transport. Using cryo-electron microscopy (cryo-EM), researchers have elucidated the structures of these transporters at high resolution, […]