Tag: chromosome separation

Emerging role of HJURP as a therapeutic target in cancers

Announcing a new publication for Acta Materia Medica journal. Holliday junction recognition protein (HJURP) is a key molecular chaperone for centromere protein A (CENP-A), which is essential for chromosome separation during mitosis and cell cycle regulation. Recent studies have identified the essential role of HJURP in carcinogenesis. Abnormal upregulation of HJURP expression has been observed […]