Tag: Celastrol

Druggability, molecular targets, and nanocarrier delivery of natural triterpenoid celastrol against chronic diseases

Announcing a new publication for Acta Materia Medica journal.  Celastrol is an active compound from the root of Tripterygium wilfordii Hook F that shows great potential in the treatment of inflammation, cancer, neurodegeneration, diabetes, and obesity. However, the clinical application of celastrol has been hindered by its low bioavailability and severe systemic toxicity. The aim of this […]