Tag: cardiovascular diseases

Targeted nanozyme-enabled treatment of cardiovascular diseases

nanozyme-enabled treatment of cardiovascular diseases

Announcing a new publication for Acta Materia Medica journal. Cardiovascular diseases (CVDs) pose a significant threat to human health due to the high mortality and morbidity rates. Traditional drugs often have limited efficacy due to inherent constraints, such as low bioavailability and notable side effects. As a highly regarded therapeutic strategy, nanotechnology offers new perspectives […]

Exploring the efficacious subfractions and underlying mechanisms of Herba Siegesbeckiae against myocardial ischemia/reperfusion injury via the UCHL5/NLRP3 pathway

Announcing a new publication for Acta Materia Medica journal.  Herba Siegesbeckiae (HS) has been traditionally used for managing cardio- and cerebro-vascular diseases. Previous studies have demonstrated that HS ameliorates myocardial ischemia/reperfusion (I/R) injury. Also, the differentially expressed proteins between HS and I/R groups were shown to be displayed as UCHL5 and were mainly enriched in […]

Identification of GPR35-associated metabolic characteristics through LC-MS/MS-based metabolomics and lipidomics

Announcing a new publication for Acta Materia Medica journal. G protein-coupled receptor 35 (GPR35) has gained increasing attention as a promising target in treating inflammatory and gastrointestinal tract conditions, cardiovascular diseases, and cancer. Metabolites including kynurenic acid, lysophosphatidic acids, chemokine 17, and 5-hydroxyindole acetic acid have been suggested to be endogenous ligands of GPR35. However, […]

Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates

Announcing a new publication for Acta Materia Medica journal.  Inflammation is an essential part of the immune response to injury and infection. Emerging evidence indicates that long-term low-grade inflammation is positively correlated with many diseases, such as cancer, metabolic disorders, and cardiovascular diseases. Due to common anti-inflammatory drugs are suitable for treating acute inflammation and […]