Tag: Breast cancer

New generation estrogen receptor-targeted agents in breast cancer

Announcing a new publication for Acta Materia Medica journal. Endocrine therapy that blocks estrogen receptor signaling has been effective for decades as a primary treatment choice for breast cancer patients expressing the estrogen receptor. However, the issue of drug resistance poses a significant clinical challenge. It is therefore critically important to create new therapeutic agents […]

Discovery of a pyridophenoselenazinium-based photosensitizer with high photodynamic efficacy against breast cancer cells

Announcing a new publication for Acta Materia Medica journal.  Development of efficient photosensitizers with minimal side effects is highly desirable for photodynamic therapy. This article reports the discovery of a novel pyridophenoselenazinium-based NIR-I photosensitizer, termed PPSe, that efficiently generated both type I and II reactive oxygen species (ROS) upon appropriate light irradiation. PPSe exhibited potent phototoxicity as well […]