Announcing a new publication for Acta Materia Medica journal. Phenanthroindolizidine alkaloids (PAs) are a series of compounds that have been isolated from traditional herbal medicines and have significant therapeutic potential, such as anti-arthritic, anti-viral, anti-inflammatory, and anti-glioma effects in vitro and in vivo. This study predicts the absorption, distribution, metabolism, excretion, and toxicity (ADMET) characteristics of 44 compounds in […]
Tag: Anti-inflammatory
Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates
Announcing a new publication for Acta Materia Medica journal. Inflammation is an essential part of the immune response to injury and infection. Emerging evidence indicates that long-term low-grade inflammation is positively correlated with many diseases, such as cancer, metabolic disorders, and cardiovascular diseases. Due to common anti-inflammatory drugs are suitable for treating acute inflammation and […]
Phenylethanoid glycoside verbascoside ameliorates podocyte injury of diabetic kidney disease by regulating NR4A1-LKB1-AMPK signaling
Announcing a new publication for Acta Materia Medica journal. Diabetic kidney disease (DKD) is one of the leading causes of end-stage renal disease. Verbascoside is a ubiquitous phenylethanoid glycoside with potent anti-inflammatory, antioxidant, and hypoglycemic properties. This paper determines the renoprotective effect of verbascoside against DKD, as well as the underlying mechanism. After administration of […]
Biothiol-triggered H2S release from a near-infrared fluorescent H2S donor promotes cutaneous wound healing
Announcing a new publication for Acta Materia Medica journal. Hydrogen sulfide (H2S) plays crucial roles in antioxidation, anti-inflammation, and cytoprotection. Despite substantial progress in the design and synthesis of activatable H2S donors, methods for high-precision detection and imaging of released H2S in living systems have been lacking. In this study, a biothiol-activated near-infrared (NIR) fluorescent […]