Category: News and Events

Baseline differences in metabolic profiles of patients with lung squamous cell carcinoma responding or not responding to treatment with nanoparticle albumin-bound paclitaxel (nab-paclitaxel)

Announcing a new publication for Acta Materia Medica journal. Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) is a preparation widely used in chemotherapy for cancers. However, only some patients benefit from this treatment. Therefore, identifying which patients will respond to nab-paclitaxel therapy is crucial. A cohort of 32 patients with lung squamous cell carcinoma (LUSC) treated with nab-paclitaxel […]

An intrinsic connection between COVID-19 and aging

Announcing a new publication for Acta Materia Medica journal. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a rapidly spreading outbreak of coronavirus disease 2019 (the COVID-19 pandemic). COVID-19 has severely affected healthcare systems worldwide, as well as the global economy, and has significantly increased morbidity and mortality rates. The majority of COVID-19-related deaths occurred […]

Acta Materia Medica now indexed by Directory of Open Access Journals (DOAJ)

We are delighted to announce that Acta Materia Medica is now indexed by the Directory of Open Access Journals (DOAJ). DOAJ is a community-curated online directory that indexes and provides access to high-quality, open access, peer-reviewed journals and has a reputation for advocating best practices and standards in open access. To be indexed within DOAJ […]

Novel emerging nano-assisted anti-cancer strategies based on the STING pathway

Announcing a new publication for Acta Materia Medica journal.  Activation of simulator of interferon genes (STING), which induces the production of proinflammatory factors and immune effector cell activation, is considered a promising strategy for enhanced anti-cancer intervention. However, several obstacles prevent STING signaling in solid tumors, such as delivered molecules’ rapid degradation, restriction to tumor […]

Cuproptosis-related MTF1 inhibits kidney renal clear cell carcinoma progression by suppressing proliferation and regulating immune cell infiltration

Announcing a new publication for Acta Materia Medica journal.  Cuproptosis is a newly identified specific form of programmed cell death. This study aims to identify cuproptosis-related genes (CRGs) in patients with kidney renal clear cell carcinoma (KIRC) from the Cancer Genome Atlas database and to evaluate CRG biological functions. Using lasso regression, four KIRC prognosis-associated […]

Senescence-associated lncRNAs indicate distinct molecular subtypes associated with prognosis and androgen response in patients with patients with prostate cancer

Announcing a new publication for Acta Materia Medica journal.  Cellular senescence has been considered as a hallmark of aging. The authors of this article aimed to establish two novel prognostic subtypes for prostate cancer patients using senescence-related lncRNAs. Nonnegative matrix factorization algorithm was used to identify molecular subtypes. Analyses were completed using software R 3.6.3 […]

Recent advances in the molecular design and applications of proteolysis targeting chimera-based multi-specific antiviral modality

Announcing a new publication for Acta Materia Medica journal. Viral infections represent a major threat to human health and the global economy; however, most of the currently available antiviral drugs are not fully effective in restricting viral replication and selecting for drug-resistant variants. Targeted protein degradation technologies are promising strategies to avoid or delay the […]

Aging and cancer hallmarks as therapeutic targets

Announcing a new publication for Acta Materia Medica journal.  The prevalence of age-related diseases has been progressively increasing worldwide. The pathogenesis of these disorders, including cancer, is closely associated with an age-dependent decline in cellular functions. There are multiple layers of crosstalk between aging processes and oncogenesis. Therefore, a better understanding of the interplay between […]

1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein

Announcing a new publication for Acta Materia Medica journal.  Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally since 2020. The nucleocapsid (N) protein plays a crucial role in the life cycle of SARS-CoV-2. The authors of this article have established a method to screen inhibitors of N protein by using microscale thermophoresis assays […]

ZnPc photosensitizer-loaded peony-shaped FeSe 2 remotely controlled by near-infrared light for antimycobacterial therapy

Announcing a new publication for Acta Materia Medica journal.      The development of novel antimicrobial agents is highly desirable for treating bacterial infections. The authors of this article constructed a smart photodynamic therapy (PDT) system based on a combination of peony-shaped ferroselite FeSe2 particles and zinc (II) phthalocyanine (ZnPc) photosensitizers. Effective energy transfer occurred from ZnPc to […]