Announcing a new publication for Acta Materia Medica journal. The concept of food and medicine homology (FMH) is deeply embedded in traditional Chinese medicine and carries historical importance.
The recent rigorous definition of FMH pertains to substances that exhibit both pharmacological and nutritional functions and have active ingredients that are fundamentally non-toxic and appropriate for extended consumption. With the progression of modern biotechnology, the application of this concept in treating diseases has markedly expanded, and its intrinsic mechanisms have been examined in detail.
The use of FMH substances in cancer therapy, as either a primary treatment or an adjuvant therapy, has paved the way to low-toxicity cancer treatments. This article examines the theoretical underpinnings, potential advantages, and practical applications of FMH substances in cancer prevention, treatment, and nutritional support enhancement. Advantages including low toxicity, long-term edibility, minimal adverse effects, and high patient compliance are discussed. Moreover, owing to its multicomponent and multitarget characteristics, FMH may provide novel opportunities for cancer therapy. Given the high lethality of cancer and associated ethical implications, current research should prioritize fundamental studies investigating potential FMH applications in cancer therapy. Concurrently, preliminary preclinical studies would be appropriate to establish a solid foundation for subsequent clinical trials.
Read full articles at ScienceOpen: https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2025-0003
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eISSN 2737-7946
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Meng-Yao Li, Ao Gu and Jiatong Li et al. Exploring food and medicine homology: potential implications for cancer treatment innovations. Acta Materia Medica. 2025. Vol. 4(2):200-206. DOI: 10.15212/AMM-2025-0003