{"id":1062,"date":"2024-03-25T09:23:34","date_gmt":"2024-03-25T09:23:34","guid":{"rendered":"https:\/\/amm-journal.org\/?p=1062"},"modified":"2024-03-25T09:23:34","modified_gmt":"2024-03-25T09:23:34","slug":"application-of-protacs-in-target-identification-and-validation","status":"publish","type":"post","link":"https:\/\/amm-journal.org\/index.php\/2024\/03\/25\/application-of-protacs-in-target-identification-and-validation\/","title":{"rendered":"Application of PROTACs in target identification and validation"},"content":{"rendered":"<p>Announcing a new publication for <em>Acta Materia Medica<\/em> journal. Proteolysis targeting chimeras (PROTACs), as a novel therapeutic drug model, has received widespread attention from academia and the pharmaceutical industry. PROTAC technology has led researchers to focus on developing chemical biology tool properties due to the unique operating mechanism and protein dynamic regulatory properties. In recent years the rapid development of PROTAC technology has gradually made PROTACs an essential tool for target identification and validation. To further promote the application of PROTAC tools in drug discovery and basic medical science research, this article distinguishes target identification and validation concepts. Furthermore, research progress in PROTAC technology is summarized.<\/p>\n<p style=\"line-height: 15.0pt; margin: 0cm 0cm 7.5pt 0cm;\"><a href=\"https:\/\/www.scienceopen.com\/hosted-document?doi=10.15212\/AMM-2024-0010\">https:\/\/www.scienceopen.com\/hosted-document?doi=10.15212\/AMM-2024-0010<\/a><\/p>\n<p><em>Acta Materia Medica<\/em> welcomes the submission of research articles, review articles, databases, mini reviews, commentaries, editorials, short communications, case report articles and study protocols.<\/p>\n<p><strong>Submission Process<\/strong><\/p>\n<p>Submissions <em>to Acta Materia Medica<\/em> are made using ScholarOne, the online submission and peer review system. Registration and access are available at <a href=\"https:\/\/mc04.manuscriptcentral.com\/ammed\">https:\/\/mc04.manuscriptcentral.com\/ammed<\/a><\/p>\n<p>Queries about the journal can be sent to editorialoffice@amm-journal.org.<\/p>\n<p>Please visit <a href=\"https:\/\/amm-journal.org\/\">https:\/\/amm-journal.org\/<\/a> to learn more about the journal.<\/p>\n<p><strong>Editorial Board:<\/strong> <a href=\"https:\/\/amm-journal.org\/index.php\/editorial-board\/\">https:\/\/amm-journal.org\/index.php\/editorial-board\/<\/a><\/p>\n<p>There are no author submission or article processing fees.<\/p>\n<p>Follow <strong><em>Acta Materia Medica <\/em><\/strong>on Twitter <a href=\"https:\/\/twitter.com\/AMM_journal\">https:\/\/twitter.com\/AMM_journal<\/a>; <a href=\"https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114\">Facebook<\/a> (<a href=\"https:\/\/www.facebook.com\/AMMjournal\">https:\/\/www.facebook.com\/AMMjournal<\/a>)<\/p>\n<p><strong>eISSN <\/strong>2737-7946<\/p>\n<p>Yang Liu, Jing Liang and Rui Zhu et al. Application of PROTACs in target identification and validation.\u00a0<em>Acta Materia Medica.\u00a0<\/em>2024. Vol. 3(1):72-87. DOI: 10.15212\/AMM-2024-0010<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Announcing a new publication for Acta Materia Medica journal. Proteolysis targeting chimeras (PROTACs), as a novel therapeutic drug model, has received widespread attention from academia and the pharmaceutical industry. PROTAC technology has led researchers to focus on developing chemical biology tool properties due to the unique operating mechanism and protein dynamic regulatory properties. In recent [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[13,261,262],"class_list":["post-1062","post","type-post","status-publish","format-standard","hentry","category-news-and-events","tag-protac","tag-proteolysis-targeting-chimeras","tag-therapeutic-drug"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Application of PROTACs in target identification and validation - AMM Journal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/amm-journal.org\/index.php\/2024\/03\/25\/application-of-protacs-in-target-identification-and-validation\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Application of PROTACs in target identification and validation - AMM Journal\" \/>\n<meta property=\"og:description\" content=\"Announcing a new publication for Acta Materia Medica journal. Proteolysis targeting chimeras (PROTACs), as a novel therapeutic drug model, has received widespread attention from academia and the pharmaceutical industry. PROTAC technology has led researchers to focus on developing chemical biology tool properties due to the unique operating mechanism and protein dynamic regulatory properties. 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